Immunodominant T-cell epitopes from the SARS-CoV-2 spike antigen reveal robust pre-existing T-cell immunity in unexposed individuals
S. Mahajan, K. Bhojak, V. Kode, C. M. Magdalene, M. Manoharan, K. Lee, A. Ramesh, S. H. V, A. Srivastava, R. Sathian, P. Kumar, T. Khan, P. Chakraborty, A. Chaudhuri
This study identifies immunodominant T-cell epitopes in SARS-CoV-2 spike antigen and shows pre-existing T-cell immunity in unexposed individuals, suggesting prior exposure to common viruses like Influenza and CMV.
bioRxiv · Nov 3, 2020Immunology