Author

S. Heitmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

J. I. Vandenberg· 3 shared A. P. Hill· 2 shared A. Hill· 1 shared J. A. Gillis· 1 shared M. D. Perry· 1 shared M. M. Mangala· 1 shared S. Ballouz· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiophysics

J. I. Vandenberg

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Assessing drug safety by identifying the axis of arrhythmia in cardiomyocyte electrophysiology

S. Heitmann, J. I. Vandenberg, A. P. Hill

The paper identifies the axis of arrhythmia, a metric to assess drug-induced arrhythmia risk using electrophysiological simulations of cardiomyocytes, achieving 88.1-90.8% accuracy in predicting clinical risk labels.

bioRxiv · Apr 19, 2023Pharmacology & Toxicology

Arrhythmogenesis as the failure of repolarization

S. Heitmann, J. I. Vandenberg, A. Hill

This paper proposes a new mechanism for arrhythmogenesis where cardiac cells failing to repolarize act as focal ectopic sources, leading to fibrillation, and shows that arrhythmia susceptibility is higher at tissue boundaries.

bioRxiv · Jul 2, 2020 · PreprintBiophysics

Co-expression of calcium channels and delayed rectifier potassium channels protects the heart from proarrhythmic events

S. Ballouz, M. M. Mangala, M. D. Perry, S. Heitmann, J. A. Gillis, A. P. Hill, J. I. Vandenberg

The paper identifies co-expression of CACNA1C and KCNH2 in cardiac cells as protective against proarrhythmic events through reduced action potential variability.

bioRxiv · Mar 11, 2020 · PreprintBiophysics