S. Hilau

Population level genetic memory of prior metabolic adaptation in E. coli

This study shows E. coli maintains genetic memory of prior metabolic adaptations, enabling rapid re-adaptation to consume butyrate after resource exhaustion.

Density-dependent effects are the main determinants of variation in growth dynamics between closely related bacterial strains

The paper models growth and death dynamics of E. coli strains, showing that density-dependent inhibition and resource efficiency, not growth/death rates, explain strain variability.

Dynamics of mutation accumulation and adaptation during three years of evolution under long-term stationary phase

This study tracks genetic adaptation and mutation dynamics in E. coli over three years in long-term stationary phase, showing convergent mutation accumulation and varying mutation rates among clones.