Stromal localization of inactive CD8+ T cells in metastatic mismatch repair deficient colorectal cancer
E. Kucukkose, M. J. D. Baars, M. Amini, S. J. Schraa, E. Floor, G. M. Bol, I. H. M. B. Rinkes, J. M. L. Roodhart, M. Koopman, J. Laoukili, O. Kranenburg, Y. Vercoulen
The paper identifies stromal localization of inactive CD8+ T cells in metastatic MSI-H CRC and links it to poor immune response.
bioRxiv · Oct 9, 2023Cancer Biology