Author

Y. Vercoulen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:spatial transcriptomics· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Marson· 1 shared D. Krijgsman· 1 shared D. R. Myers· 1 shared D. R. Simeonov· 1 shared E. Duiker· 1 shared E. Floor· 1 shared E. Kucukkose· 1 shared F. van Wijk· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

A. Marson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Stromal localization of inactive CD8+ T cells in metastatic mismatch repair deficient colorectal cancer

E. Kucukkose, M. J. D. Baars, M. Amini, S. J. Schraa, E. Floor, G. M. Bol, I. H. M. B. Rinkes, J. M. L. Roodhart, M. Koopman, J. Laoukili, O. Kranenburg, Y. Vercoulen

The paper identifies stromal localization of inactive CD8+ T cells in metastatic MSI-H CRC and links it to poor immune response.

bioRxiv · Oct 9, 2023Cancer Biology

Hepatoblastoma exhibits a predominantly myeloid immune landscape and reveals opportunities for macrophage targeted immunotherapy

D. Krijgsman, L. Kraaier, M. Verdonschot, S. Schubert, J. Leusen, E. Duiker, R. de Kleine, V. de Meijer, R. de Krijger, J. Zsiros, W. C. Peng, Y. Vercoulen

This paper characterizes the immune landscape of hepatoblastoma, revealing a myeloid-dominated environment with limited T cells and opportunities for macrophage-targeted immunotherapy.

bioRxiv · Jun 28, 2023Cancer Biology

Dysregulated RASGRP1 expression through RUNX1 mediated transcription promotes autoimmunity

M. Baars, T. Douma, D. R. Simeonov, D. R. Myers, S. Banerjee, K. Kulhanek, S. Zwakenberg, M. P. Baltissen, S. de Roock, F. van Wijk, M. Vermeulen, A. Marson, J. P. Roose, Y. Vercoulen

The paper shows that reduced RASGRP1 expression, regulated by RUNX1, contributes to autoimmunity by impairing T cell function and increasing inflammation.

bioRxiv · Nov 8, 2019Immunology