Alpha-2 agonism of the locus coeruleus impairs learning driven by negative prediction error
Ashleigh K. Brink, S. K. C. Lui, Laura H. Corbit
This study shows that LC activity is crucial for learning to reduce responding in both extinction and overexpectation paradigms, as clonidine impaired these processes.
Neuropsychopharmacology · Apr 13, 2025Peer-reviewedAnimal Behavior & Cognition