Co-aggregation and secondary nucleation in the life cycle of human prolactin/galanin functional amyloids
D. Chatterjee, R. S. Jacob, S. Ray, A. Navalkar, N. Singh, S. Sengupta, L. Gadhe, P. Kadu, D. Datta, A. Paul, C. Pindi, S. Kumar, P. S. Singru, S. K. Senapati, S. K. Maji
This study investigates co-aggregation and cross-seeding between prolactin and galanin in rat lactotrophs, revealing a novel mechanism of heterologous amyloid formation with implications for functional and pathological amyloids.
bioRxiv · Aug 31, 2021Biophysics