Degree and site of chromosomal instability define its oncogenic potential
W. Hoevenaar, A. Janssen, A. Quirindongo, H. Ma, S. Klaasen, A. Teixeira, J. Offerhaus, R. Medema, G. Kops, N. Jelluma
This study shows that chromosomal instability (CIN) can drive early-onset intestinal adenomas, with varying effects depending on CIN levels and tissue site.
bioRxiv · Dec 15, 2019Cancer Biology