Variations in cellular unfolded protein response, respiratory capacity, and stress tolerance in skin and lung fibroblasts of deer mice (Peromyscus maniculatus)
K. N. Yap, K. Yamada, S. L. Zikeli, Y. Zhang, Y. Zhang, A. Naderi, E. Soltanmohammadi, A. N. Kavazis, M. D. Roberts, H. Kiaris, W. R. Hood
This study examines UPR, respiratory capacity, and stress tolerance in skin and lung fibroblasts of deer mice, finding only tunicamycin-induced BiP expression is repeatable across cell types and predicts stress resistance and bioenergetics.
bioRxiv · Dec 7, 2023 · PreprintPhysiology