Author

S. M. Prince

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

A. Barbieri· 1 shared C. Baldock· 1 shared C. Levy· 1 shared J. Chipperfield· 1 shared L. Bird· 1 shared M. P. Lockhart-Cairns· 1 shared N. A. Rodzli· 1 shared N. Thonghin· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Barbieri

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2 papers

Recent·Most cited

Structure of ABCB1/P-glycoprotein bound to the CFTR potentiator ivacaftor.

A. Barbieri, N. Thonghin, T. Shafi, S. M. Prince, R. F. Collins, R. C. Ford

This study determines the structure of ABCB1/P-glycoprotein bound to ivacaftor and compares it to the drug-free state to understand binding mechanisms and conformational changes.

bioRxiv · Jun 11, 2021 · PreprintBiochemistry

How the dual PDZ domain from Postsynaptic density protein 95 clusters ion channels and receptors.

N. A. Rodzli, M. P. Lockhart-Cairns, C. Levy, J. Chipperfield, L. Bird, C. Baldock, S. M. Prince

This study reports crystal structures and thermodynamic analysis of the dual PDZ domain of PSD-95, revealing its scaffolding function in clustering ion channels and receptors.

bioRxiv · Sep 19, 2019 · PreprintBiophysics