A role for SHARPIN in platelet linear protein ubiquitination and function
S. F. Moore, X. Zhao, S. Mallah, A. W. Poole, S. J. Mundell, J. L. Hutchinson, I. Hers
This study shows that SHARPIN is essential for platelet linear ubiquitination and function, particularly in responses to CRP and U46619, with impaired thrombosis in SHARPIN-deficient mice.
bioRxiv · Jan 13, 2021 · PreprintCell Biology