Pharmacology & ToxicologybioRxiv
Biological Evaluation of Molecules of the azaBINOL Class as Antiviral Agents: Specific Inhibition of HIV-1 RNase H Activity by 7-Isopropoxy-8-(naphth-1-yl)quinoline
R. D. Overacker, S. Banerjee, G. F. Neuhaus…·S. Loesgen
This study evaluates azaBINOL compounds as antiviral agents, identifying 7-isopropoxy-8-(naphth-1-yl)quinoline as a low-micromolar inhibitor of HIV-1 RNase H activity.
DOI 10.1016/j.bmc.2019.06.044