CryoEM structure of the EBV ribonucleotide reductase BORF2 and mechanism of APOBEC3B inhibition
N. Shaban, R. Yan, K. Shi, S. Moraes, A. Cheng, M. Carpenter, J. S. McLellan, Y. Zhiheng, R. Harris
This study reveals how EBV's BORF2 protein inhibits APOBEC3B by blocking its access to DNA, providing insights for drug development.
bioRxiv · Aug 30, 2021 · PreprintMicrobiology