Author

S. Mosure

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

D. Kojetin· 1 shared J. Shang· 1 shared J. Zheng· 1 shared P. Griffin· 1 shared R. Brust· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBiochemistry

D. Kojetin

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1 paper

Recent·Most cited

Structural basis of altered potency and efficacy displayed by a major in vivo metabolite of the anti-diabetic PPARγ drug pioglitazone

S. Mosure, J. Shang, R. Brust, J. Zheng, P. Griffin, D. Kojetin

This study compares the structure and function of pioglitazone and its metabolite 1-hydroxypioglitazone bound to PPARγ, showing reduced potency and efficacy of the metabolite.

bioRxiv · Aug 13, 2018Biochemistry