Author

S. Mühlen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

P. Dersch· 2 shared A. Steffen· 1 shared C. Rueter· 1 shared E. M. Gazdag· 1 shared L. Jansch· 1 shared M. Kirchenwitz· 1 shared P. Chaoprasid· 1 shared P. Lukat· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

P. Dersch

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Identification of translocation inhibitors targeting the type III secretion system of enteropathogenic E. coli

S. Mühlen, V. Zapolskii, U. Bilitewski, P. Dersch

This study identifies three compounds that inhibit T3SS-mediated effector translocation in EPEC without affecting bacterial viability or T3SS components.

bioRxiv · May 11, 2021Microbiology

Crystal structure of full-length cytotoxic necrotizing factor CNFY reveals molecular building blocks for intoxication

P. Chaoprasid, P. Lukat, S. Mühlen, T. V. Heidler, E. M. Gazdag, S. Dong, W. Bi, C. Rueter, M. Kirchenwitz, A. Steffen, L. Jansch, T. Stradal, P. Dersch, W. Blankenfeldt

The paper determines the crystal structure of CNFY, revealing domains involved in toxin translocation and identifying its potential as a drug delivery tool.

bioRxiv · Apr 7, 2020Biochemistry