P. Dersch

RNase-mediated reprogramming of Yersinia virulence

This study identifies RNase III and PNPase as key regulators of virulence gene expression in Yersinia pseudotuberculosis by modulating lcrF mRNA stability and translation.

Infection and antibiotic-associated changes in the fecal microbiota of C. rodentium {Phi}stx2dact-infected C57BL/6 mice

This paper examines how C. rodentium {phi}stx2dact infection and antibiotic treatment affect fecal microbiota in mice, finding that antibiotics causing rapid infection clearance have the most detrimental impact on microbiota diversity.

Clathrin-independent endocytosis of Human Papillomaviruses is facilitated by actin nucleation promoting factor WASH

This study identifies WASH as a facilitator of clathrin-independent endocytosis of HPV16, independent of retromer and SNX-BAR.

The gatekeeper of Yersinia type III secretion is under RNA thermometer control

This paper shows that YopN, a gatekeeper for Yersinia type III secretion, is regulated by an RNA thermometer that controls translation at 37°C, ensuring controlled effector protein secretion.

Identification of translocation inhibitors targeting the type III secretion system of enteropathogenic E. coli

This study identifies three compounds that inhibit T3SS-mediated effector translocation in EPEC without affecting bacterial viability or T3SS components.

Crystal structure of full-length cytotoxic necrotizing factor CNFY reveals molecular building blocks for intoxication

The paper determines the crystal structure of CNFY, revealing domains involved in toxin translocation and identifying its potential as a drug delivery tool.

Bread feeding is a robust and more physiological enteropathogen administration method compared to oral gavage

This study compares bread feeding to oral gavage for administering Yersinia pseudotuberculosis, finding bread feeding is more physiological, less traumatic, and results in more accurate intestinal infection models.

The alarmone (p)ppGpp is part of the heat shock response of Bacillus subtilis

This study shows that (p)ppGpp, a bacterial alarmone, mediates the heat shock response in B. subtilis by reducing translation and enhancing stress tolerance.