pADP-ribosylation Regulates the Cytoplasmic Localization, Cleavage and Pro-apoptotic Function of HuR
K. Ashour, D. T. Hall, S. Mubaid, S. Bousque, X. Lian, J.-P. Gagne, S. Khattak, S. Di Marco, G. Poirier, I. E. Gallouzi
This study shows that PARP1/2-mediated PARylation regulates HuR's nuclear localization, cleavage, and pro-apoptotic function by binding to the HuR-PBS motif.
bioRxiv · Aug 7, 2023Cell Biology