Author

J.-P. Gagne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:Drosophila· 1

Frequent Co-Authors

G. G. Poirier· 2 shared G. Poirier· 2 shared A. Pascal· 1 shared A. R. Fehr· 1 shared A. Roy· 1 shared B. G. Kang· 1 shared C. Benaud· 1 shared D. Chretien· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBiochemistry

G. G. Poirier

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

pADP-ribosylation Regulates the Cytoplasmic Localization, Cleavage and Pro-apoptotic Function of HuR

K. Ashour, D. T. Hall, S. Mubaid, S. Bousque, X. Lian, J.-P. Gagne, S. Khattak, S. Di Marco, G. Poirier, I. E. Gallouzi

This study shows that PARP1/2-mediated PARylation regulates HuR's nuclear localization, cleavage, and pro-apoptotic function by binding to the HuR-PBS motif.

bioRxiv · Aug 7, 2023Cell Biology

Proteome-wide microarray-based screening of PAR-binding proteins

B. G. Kang, S.-U. Kang, J. J. Kim, J.-S. Kwon, J.-P. Gagne, S. Y. Lee, S. Kim, K. L. Sangwon, S. Ha, J. S. Jeong, Y.-I. Lee, H. Zhu, D. Kim, G. G. Poirier, H. C. Kang, , T. M. Dawson

The paper identifies 356 PAR-binding proteins using a human protein microarray, revealing new biological roles of PARylation beyond DNA repair.

bioRxiv · Jun 6, 2022Biochemistry

The SARS-CoV-2 conserved macrodomain is a mono-ADP-ribosylhydrolase

Y. M. O. Alhammad, M. M. Kashipathy, A. Roy, J.-P. Gagne, P. McDonald, P. Gao, L. Nonfoux, K. P. Battaile, D. K. Johnson, E. D. Holmstrom, G. G. Poirier, S. W. Lovell, A. R. Fehr

This paper identifies SARS-CoV-2's Mac1 as a mono-ADP-ribosylhydrolase, showing it binds and hydrolyzes mono-ADP-ribose, with implications for antiviral therapy.

bioRxiv · May 11, 2020Biochemistry

Drosophila dTBCE recruits tubulin around chromatin to promote mitotic spindle assembly

M. Metivier, E. Gallaud, A. Pascal, J.-P. Gagne, G. Poirier, D. Chretien, R. Gibeaux, L. Richard-Parpaillon, C. Benaud, R. Giet

The paper identifies dTBCE's role in promoting mitotic spindle assembly by recruiting tubulin around chromatin in Drosophila.

bioRxiv · Jan 21, 2020Cell Biology