PDEδ inhibition impedes the proliferation and survival of human colorectal cancer cell lines harboring oncogenic KRas
C. H. Klein, D. C. Truxius, H. A. Vogel, J. Harizanova, S. Murarka, P. Martin-Gago, P. Bastiaens
This study shows that PDEδ inhibition specifically reduces proliferation and survival of colorectal cancer cells with oncogenic KRas mutations, but not those with wild-type KRas or other mutations.
bioRxiv · Jul 25, 2018Cell Biology