Author

S. Nomikou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:deep learning· 2 Assay:Hi-C· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Tsirigos· 3 shared I. Aifantis· 2 shared T. Lionnet· 2 shared Y. Fu· 2 shared A. Hatzimemos· 1 shared A. Kloetgen· 1 shared C. Lazaris· 1 shared D. Donnelly· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersBiophysics

A. Tsirigos

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Connecting Chromatin Structures to Gene Regulation Using Dynamic Polymer Simulations

Y. Fu, T. Zhao, F. T. Clark, S. Nomikou, A. Tsirigos, T. Lionnet

The paper uses polymer simulations to model chromatin dynamics and shows that productive interactions depend on contact frequency, capture radius, and duration, not just average contact matrices.

bioRxiv · Nov 7, 2023 · PreprintBiophysics

A Deep Learning Approach for Rapid Mutational Screening in Melanoma

R. Kim, S. Nomikou, N. Coudray, G. Jour, Z. Dawood, R. Hong, E. Esteva, T. Sakellaropoulos, D. Donnelly, U. Moran, A. Hatzimemos, J. S. Weber, N. Razavian, I. Aifantis, D. Fenyo, , A. Tsirigos

This paper develops a deep learning model to detect BRAF mutations in melanoma histopathology images using whole slide images from 256 patients, achieving AUC scores of 0.96 and 0.72.

bioRxiv · Aug 19, 2020 · PreprintPathology

Dynamic 3D chromosomal landscapes in acute leukemia

A. Kloetgen, P. Thandapani, P. Ntziachristos, Y. Ghebrechristos, S. Nomikou, C. Lazaris, X. Chen, H. Hu, S. Bakogianni, J. Wang, Y. Fu, F. Boccalatte, H. Zhong, E. Paietta, T. Trimarchi, , A. Tsirigos

The paper examines 3D chromatin changes in T-ALL, identifies TAD fusion events linked to oncogene activation, and shows drug treatments can restore some interactions.

bioRxiv · Aug 4, 2019Cancer Biology