BiophysicsbioRxivPreprint
Dynamic changes in β-cell electrical activity and regulates NFATc3 activation and downstream gene transcription
J. G. Miranda, W. E. Schleicher, D. G. Ramirez…·R. K. Benninger
This study investigates how dynamic changes in β-cell electrical activity and calcium oscillations regulate NFAT activation and downstream gene transcription, showing impaired responses in type 2 diabetes.