Author

S. P. Persaud

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

J. F. DiPersio· 2 shared J. K. Ritchey· 2 shared M. P. Rettig· 2 shared A. R. Yelamali· 1 shared E. Chendamarai· 1 shared J. Choi· 1 shared M. L. Cooper· 1 shared P. G. Ruminski· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 22 mutual co-author links

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2 shared papersImmunology

J. F. DiPersio

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2 papers

Recent·Most cited

Streptavidin-drug conjugates streamline optimization of antibody-based conditioning for hematopoietic stem cell transplantation

A. R. Yelamali, E. Chendamarai, J. K. Ritchey, M. P. Rettig, J. F. DiPersio, S. P. Persaud

This paper develops a streptavidin-drug conjugate platform to efficiently optimize antibody-based conditioning for HSCT, finding that PBD dimer SGD-1882 is most effective for targeting HSCs and AML cells.

bioRxiv · Feb 12, 2024Immunology

Antibody-drug conjugates targeting CD45 plus Janus kinase inhibitors effectively condition for allogeneic hematopoietic stem cell transplantation

S. P. Persaud, J. K. Ritchey, J. Choi, P. G. Ruminski, M. L. Cooper, M. P. Rettig, J. F. DiPersio

This study shows that combining CD45-targeted ADCs with baricitinib enables effective allogeneic HSCT with high donor chimerism and reduced graft-versus-host disease.

bioRxiv · Oct 2, 2020Immunology