The lamellipodium is a myosin independent mechanosensor
P. W. Oakes, T. C. Bidone, Y. Beckham, A. V. Skeeters, G. R. Ramirez-San Juan, S. P. Winter, G. A. Voth, M. L. Gardel
This paper shows that cell spreading on soft substrates is inhibited by reduced adhesion formation in the lamellipodium, independent of myosin II activity.
bioRxiv · Sep 8, 2017Biophysics