Monoclonal antibodies targeting surface exposed epitopes of Candida albicans cell wall proteins confer in vivo protection in an infection model
S. Palliyil, M. Mawer, S. Alwafi, L. Fogg, G. Buda De Cesare, T. Tan, L. A. Walker, D. MacCallum, A. Porter, C. A. Munro
The paper develops monoclonal antibodies targeting Candida albicans cell wall proteins that show improved survival and fungal burden reduction in mouse models of systemic candidiasis.
bioRxiv · Sep 29, 2021Microbiology