Author

L. A. Walker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 2 Animal Behavior & Cognition· 1 Bioengineering· 1 Physiology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Approach:statistical model· 2

Frequent Co-Authors

Y. Du· 3 shared C. A. Munro· 2 shared P. M. Buttrick· 2 shared A. Bojarczuk· 1 shared A. C. Drotos· 1 shared A. D'Alessandro· 1 shared A. Kriebel· 1 shared A. Porter· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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3 shared papersBioengineering

Y. Du

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Dynamically stiffening biomaterials reveal age- and sex-specific differences in pulmonary arterial adventitial fibroblast activation

M. C. Mueller, Y. Du, L. A. Walker, C. M. Magin

This study uses dynamic biomaterials to show age and sex differences in hPAAF activation in response to stiffness, linking findings to the estrogen paradox in PAH.

bioRxiv · May 11, 2023Bioengineering

Monoclonal antibodies targeting surface exposed epitopes of Candida albicans cell wall proteins confer in vivo protection in an infection model

S. Palliyil, M. Mawer, S. Alwafi, L. Fogg, G. Buda De Cesare, T. Tan, L. A. Walker, D. MacCallum, A. Porter, C. A. Munro

The paper develops monoclonal antibodies targeting Candida albicans cell wall proteins that show improved survival and fungal burden reduction in mouse models of systemic candidiasis.

bioRxiv · Sep 29, 2021Microbiology

Prolactin and the shared regulation of parental care and cooperative helping in white-browed sparrow weaver societies

L. A. Walker, L. Tschirren, J. E. York, P. J. Sharp, S. L. Meddle, A. Young

This study examines how prolactin levels correlate with parental and helper provisioning behavior in white-browed sparrow weavers, suggesting a shared regulatory mechanism for parental care and cooperative helping.

bioRxiv · Sep 22, 2021 · PreprintAnimal Behavior & Cognition

Teaching Python for Data Science: Collaborative development of a modular & interactive curriculum

M. Duda, K. L. Sovacool, N. Farzaneh, V. K. Nguyen, S. E. Haynes, H. Falk, K. L. Furman, L. A. Walker, R. Diao, M. Oneka, A. C. Drotos, A. Woloshin, G. A. Dotson, A. Kriebel, L. Meng, , B. N. Wolford

The paper describes the development of an open-source, modular Python data science curriculum for high school women using Jupyter notebooks and collaborative practices.

bioRxiv · Jun 17, 2021Scientific Communication & Education

Isoform-specific regulation of HCN4 channels by a family of endoplasmic reticulum proteins

C. H. Peters, M. E. Myers, J. Juchno, C. Haimbaugh, H. Bichraoui, Y. Du, J. R. Bankston, L. A. Walker, C. Proenza

This paper identifies two ER proteins, LRMP and IRAG, that modulate HCN4 channel function differently, with LRMP inhibiting and IRAG enhancing HCN4 activity in a cAMP-independent manner.

bioRxiv · Apr 10, 2020Physiology

Maturation of human induced pluripotent stem cell-derived cardiomyocytes for modeling hypertrophic cardiomyopathy

W. E. Knight, Y. Cao, Y.-H. Lin, G. C. Sparagna, B. Bai, Y. Zhao, C. Chi, Y. Du, P. Londono, J. A. Reisz, B. C. Brown, M. R. G. Taylor, A. V. Ambardekar, J. C. Cleveland, T. A. McKinsey, , K. Song

This study develops a method to mature hiPSC-CMs, enabling them to model adult-onset cardiovascular disease like hypertrophic cardiomyopathy.

bioRxiv · Jan 16, 2020Cell Biology

Intense light-mediated circadian cardioprotection via transcriptional reprogramming of the endothelium

Y. Oyama, C. M. Bartman, S. Bonnie, J. S. Lee, L. A. Walker, J. Han, C. H. Borchers, P. M. Buttrick, C. Aherne, N. Clendenen, S. P. Colgan, T. Eckle

This study identifies circadian PER2 amplitude enhancement in endothelial cells as a novel cardioprotective strategy that mimics HIF1A metabolic adaptation during myocardial ischemia.

bioRxiv · Jul 12, 2019Cell Biology

Inhibition of classical and alternative modes of respiration in C. albicans leads to cell wall remodelling and increased macrophage recognition

L. Duvenage, L. A. Walker, A. Bojarczuk, S. A. Johnston, D. M. MacCallum, C. A. Munro, C. Gourlay

This paper inhibits respiration in C. albicans using low-toxicity chemicals, leading to cell wall changes and increased macrophage recognition, but also enhancing virulence.

bioRxiv · May 24, 2018Microbiology