The E2 SUMO-conjugating enzyme UBE2I coordinates the oocyte and zygotic transcriptional programs
S. M. Briley, A. A. Ahmed, P. Jiang, S. M. Hartig, K. Schindler, S. Pangas
This study shows that oocyte-specific deletion of Ube2i leads to meiotic arrest, defective spindles, and premature zygotic transcriptional activation in mice.
bioRxiv · Dec 6, 2022 · PreprintCell Biology