Author

S. Pedretti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:metabolomics· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

F. Sciarretta· 2 shared K. AQUILANO· 2 shared M. Tiberi· 2 shared N. Mitro· 2 shared R. Turchi· 2 shared A. Chopra· 1 shared A. FERRI· 1 shared A. Gibson· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersPhysiology

F. Sciarretta

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Multiomic single-cell sequencing defines tissue-specific responses in Stevens-Johnson Syndrome and Toxic epidermal necrolysis.

A. Gibson, R. Ram, R. Gangula, Y. Li, E. Mukherjee, A. M. Palubinsky, C. N. Campbell, M. Thorne, K. C. Konvinse, P. Choshi, P. Deshpande, S. Pedretti, R. T. O'Neil, C. N. Wanjalla, S. A. Kalams, , E. J. Phillips

The paper uses multiomic single-cell sequencing to analyze SJS/TEN patients' skin and blister fluid, identifying tissue-specific immune responses and T-cell clonotypes involved in pathogenesis.

bioRxiv · Nov 26, 2023Immunology

Frataxin Deficiency Drives a Shift from Mitochondrial Metabolism to Glucose Catabolism, Triggering an Inflammatory Phenotype in Microglia

F. Sciarretta, F. Zaccaria, A. Ninni, V. Ceci, R. Turchi, S. Apolloni, V. Chiurchiu, M. Tiberi, N. D'Ambrosi, S. Pedretti, N. Mitro, K. AQUILANO, D. Lettieri Barbato, I. Della Valle, M. Milani

This study shows that frataxin deficiency in microglia shifts metabolism to glucose catabolism, causing inflammation, which is mitigated by butyrate treatment.

bioRxiv · Oct 18, 2023Physiology

Butyrate prevents visceral adipose tissue inflammation and metabolic alterations in a mouse model of Friedreich's ataxia

R. TURCHI, F. SCIARRETTA, M. TIBERI, M. AUDANO, S. PEDRETTI, C. PANEBIANCO, V. NESCI, V. PAZIENZA, A. FERRI, S. CAROTTI, V. CHIURCHIU', N. MITRO, D. LETTIERI-BARBATO, K. AQUILANO

bioRxiv · Apr 6, 2023Biochemistry