Structural basis for the activation of CDK7 by MAT1 and Cyclin H
S. Peissert, A. Schlosser, R. Kendel, J. Kuper, C. Kisker
The paper solves the structure of the CAK complex from C. thermophilum and shows MAT1-dependent CDK7 activation independent of T-loop phosphorylation.
bioRxiv · Aug 20, 2020Biochemistry