Inhibition of potassium ion channels reduces Semliki Forest virus genome replication
T. Russell, C. O'Brien, D. Gangotia, S. Fulford, R. Kenny, a. Alkhamees, S. Premchand-Branker, R. Fragkoudis, D. Scholz, G. Barry
This study shows that K+ channel inhibitors reduce SFV replication and cytotoxicity in vitro by disrupting an early post-entry step, suggesting potential for antiviral repurposing.
bioRxiv · May 24, 2023 · PreprintMicrobiology