Author

S. R. Chapin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Approach:Bayesian inference· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. J. Pattinson· 2 shared H. V. Meyer· 2 shared A. A. Minervina· 1 shared A. Axhemi· 1 shared A. Banerjee· 1 shared C. Barton· 1 shared C. L. Wincek· 1 shared G. He· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

D. J. Pattinson

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2 papers

Recent·Most cited

Comprehensive epitope mutational scan database enables accurate T cell receptor cross-reactivity prediction

A. Banerjee, D. J. Pattinson, C. L. Wincek, P. Bunk, A. Axhemi, S. R. Chapin, S. Navlakha, H. V. Meyer

The paper introduces a database of TCR-peptide mutational assays and a Bayesian model to predict TCR cross-reactivity, showing improved performance over existing methods.

bioRxiv · Jan 22, 2024 · PreprintImmunology

Identification of Antigen-Specific T Cell Receptors with combinatorial peptide pooling

V. A. Kovaleva, D. J. Pattinson, G. He, C. Barton, S. R. Chapin, A. A. Minervina, Q. Huang, P. G. Thomas, M. V. Pogorelyy, H. V. Meyer

This paper introduces copepodTCR, a tool for designing and interpreting TCR specificity assays, which efficiently identifies antigen-specific TCRs using combinatorial peptide pooling and Bayesian modeling.

bioRxiv · Nov 28, 2023 · PreprintImmunology