Author

D. J. Pattinson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Assay:proteomics· 4 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Organism:rat· 2 Approach:Bayesian inference· 1 Research Focus:benchmarking· 1

Frequent Co-Authors

A. J. Birkett· 2 shared A. M. Lias· 2 shared A. R. Noe· 2 shared B. G. Williams· 2 shared C. A. Long· 2 shared C. A. Rigby· 2 shared C. R. King· 2 shared D. Pulido· 2 shared

Activity by Year

2023-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

A. J. Birkett

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Author profile →

4 papers

Recent·Most cited

Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex

B. G. Williams, L. D. W. King, D. Pulido, D. Quinker, A. M. Lias, S. E. Silk, R. J. Ragotte, H. Davies, J. R. Barrett, K. McHugh, C. A. Rigby, D. G. W. Alanine, L. Barfod, M. W. Shea, L. A. Cowley, , S. J. Draper

This paper develops a combination malaria vaccine targeting the RCR-complex by fusing epitopes from RIPR to CyRPA, improving in vitro growth inhibition compared to RH5.1 alone.

Nature Communications · Jun 7, 2024Peer-reviewedImmunology

Comprehensive epitope mutational scan database enables accurate T cell receptor cross-reactivity prediction

A. Banerjee, D. J. Pattinson, C. L. Wincek, P. Bunk, A. Axhemi, S. R. Chapin, S. Navlakha, H. V. Meyer

The paper introduces a database of TCR-peptide mutational assays and a Bayesian model to predict TCR cross-reactivity, showing improved performance over existing methods.

bioRxiv · Jan 22, 2024 · PreprintImmunology

Preclinical Development of a Stabilized RH5 Virus-Like Particle Vaccine that Induces Improved Anti-Malarial Antibodies

L. D. W. King, D. Pulido, J. R. Barrett, H. Davies, D. Quinkert, A. M. Lias, S. E. Silk, D. J. Pattinson, A. Diouf, B. G. Williams, K. McHugh, A. Rodrigues, C. A. Rigby, V. Strazza, J. Suurbaar, , S. J. Draper

This paper develops a stabilized RH5 VLP vaccine that induces improved anti-malarial antibodies compared to a soluble protein vaccine in preclinical studies.

bioRxiv · Jan 4, 2024Immunology

Identification of Antigen-Specific T Cell Receptors with combinatorial peptide pooling

V. A. Kovaleva, D. J. Pattinson, G. He, C. Barton, S. R. Chapin, A. A. Minervina, Q. Huang, P. G. Thomas, M. V. Pogorelyy, H. V. Meyer

This paper introduces copepodTCR, a tool for designing and interpreting TCR specificity assays, which efficiently identifies antigen-specific TCRs using combinatorial peptide pooling and Bayesian modeling.

bioRxiv · Nov 28, 2023 · PreprintImmunology