Author

S. R. Farmer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:scRNA-seq· 3 Research Focus:cell-cell communication· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

N. Rabhi· 3 shared B. N. Cortez· 2 shared A. Belkina· 1 shared C. A. Biagi· 1 shared C. P. Alves· 1 shared D. Kathleen· 1 shared D. Lama· 1 shared F. Henriques· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersCell Biology

N. Rabhi

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Author profile →

4 papers

Recent·Most cited

Pathological beige remodeling induced by cancer cachexia depends on the disease severity and involves mainly the trans-differentiation of mature white adipocytes

K. B. N. H. Santos, P. Knobl, F. Henriques, M. A. Lopes, F. O. Franco, L. L. Bueno, S. R. Farmer, M. Batista

This study investigates beige remodeling in cancer cachexia, showing it depends on disease severity and involves transdifferentiation of mature white adipocytes.

bioRxiv · Sep 18, 2023 · PreprintCell Biology

Adrenergic Reprogramming of Preexisting Adipogenic Trajectories Steer Naive Mural Cells Toward Beige Differentiation

D. Kathleen, B. N. Cortez, J. Z. Lin, D. Lama, M. D. Layne, S. R. Farmer, N. Rabhi

The paper shows that cold or β3-adrenoceptor activation reprograms adipogenic trajectories in vascular mural cells to generate beige adipocytes through Adrb3 and Adrb1 activation.

bioRxiv · Aug 26, 2023 · PreprintCell Biology

Multidimensional Single-Nuclei RNA-Seq Reconstruction of Adipose Tissue Reveals Adipocyte Plasticity Underlying Thermogenic Response

C. A. Biagi, S. S. Cury, C. P. Alves, N. Rabhi, W. A. Silva, S. R. Farmer, R. F. Carvalho, M. L. Batista

This study reanalyzes single-nuclei RNA-seq data from adipose tissue to identify adipocyte subtypes and transcriptional changes during thermogenic response.

bioRxiv · Feb 16, 2021Cell Biology

Single cell atlas of beige remodeling of white adipose tissue reveals a myeloid to lymphoid shift during cold exposure compared to beta 3 adrenergic stimulation

S. R. Farmer, N. Rabhi, A. Belkina, K. Desevin, B. N. Cortez

This study compares cellular changes in white adipose tissue during cold exposure and beta 3 adrenergic stimulation using single-cell RNA sequencing, revealing distinct immune cell shifts and pathway activations.

bioRxiv · May 30, 2020 · PreprintCell Biology