Author

M. D. Layne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

A. Luebbers· 1 shared B. N. Cortez· 1 shared C. E. Philibert· 1 shared D. Kathleen· 1 shared D. Lama· 1 shared E. Green· 1 shared H. Zhang· 1 shared J. C. Wu· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Luebbers

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Direct interrogation of context-dependent GPCR activity with a universal biosensor platform

R. Janicot, M. Maziarz, J.-C. Park, A. Luebbers, E. Green, J. Zhao, C. E. Philibert, H. Zhang, M. D. Layne, J. C. Wu, M. Garcia-Marcos

The paper develops a biosensor platform to measure GPCR activity in various contexts, revealing insights into coupling selectivity, pharmacogenomics, and signaling bias.

Cell · Mar 1, 2024Peer-reviewedBiochemistry

Adrenergic Reprogramming of Preexisting Adipogenic Trajectories Steer Naive Mural Cells Toward Beige Differentiation

D. Kathleen, B. N. Cortez, J. Z. Lin, D. Lama, M. D. Layne, S. R. Farmer, N. Rabhi

The paper shows that cold or β3-adrenoceptor activation reprograms adipogenic trajectories in vascular mural cells to generate beige adipocytes through Adrb3 and Adrb1 activation.

bioRxiv · Aug 26, 2023 · PreprintCell Biology