SNCAE46K transgenic Drosophila Model of Parkinsons Disease Confirmed the Causative Role of Oxidative Stress
Samaneh Reiszadeh Jahromi, S. R. Ramesh, David Isaac Finkelstein, Mohammad Haddadi
This study creates a Drosophila model overexpressing the E46K mutant SNCA gene, confirming its role in inducing oxidative stress and neurodegeneration associated with Parkinson's disease.
bioRxiv · Feb 28, 2020 · PreprintNeuroscience