Structural insights into the mechanism of the sodium/iodide symporter (NIS)
S. Ravera, J. P. Nicola, G. Salazar de Simone, F. J. Sigworth, E. Karakas, L. M. Amzel, M. A. Bianchet, N. Carrasco
This study reports three cryo-EM structures of rat NIS, revealing substrate binding sites and transport mechanisms, and provides insights into anion selection and translocation.
bioRxiv · Apr 7, 2022Biophysics