Screening of SARS-CoV-2 Antivirals Through a Cell-Based RNA-Dependent RNA Polymerase (RdRp) Reporter Assay
T. Uppal, K. Tuffo, S. Khaiboullina, S. Reganti, M. C. PANDORI, S. C. Verma
This study develops a cell-based assay to screen SARS-CoV-2 RdRp inhibitors, showing dasabuvir effectively inhibits RdRp activity and viral replication in cell culture.
bioRxiv · Apr 4, 2022Microbiology