Author

T. Uppal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

S. C. Verma· 3 shared S. Khaiboullina· 2 shared K. Tuffo· 1 shared M. C. PANDORI· 1 shared N. Dhabarde· 1 shared P. Dabral· 1 shared S. Reganti· 1 shared V. Subramanian· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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3 shared papersMicrobiology

S. C. Verma

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

RecQ1 helicase unwinds G-Quadruplexes at oriLyt to facilitate KSHV Lytic DNA Replication

P. Dabral, T. Uppal, S. C. Verma

This study identifies G-quadruplex structures in the KSHV oriLyt region and shows that RecQ1 helicase unwinds them to facilitate lytic DNA replication.

bioRxiv · Dec 26, 2022 · PreprintMicrobiology

Screening of SARS-CoV-2 Antivirals Through a Cell-Based RNA-Dependent RNA Polymerase (RdRp) Reporter Assay

T. Uppal, K. Tuffo, S. Khaiboullina, S. Reganti, M. C. PANDORI, S. C. Verma

This study develops a cell-based assay to screen SARS-CoV-2 RdRp inhibitors, showing dasabuvir effectively inhibits RdRp activity and viral replication in cell culture.

bioRxiv · Apr 4, 2022Microbiology

In Vitro Inactivation of Human Coronavirus by Titania Nanoparticle Coatings and UVC Radiation: Throwing Light on SARS-CoV-2

S. Khaiboullina, T. Uppal, N. Dhabarde, V. Subramanian, S. C. Verma

This study investigates the virucidal efficacy of titania nanoparticles under UV radiation against HCoV-NL63, a close relative of SARS-CoV-2, using RT-PCR and virus culture assays.

bioRxiv · Aug 25, 2020Microbiology