Cell BiologybioRxiv
The encephalomyocarditis virus Leader promotes the release of virions inside extracellular vesicles via the induction of secretory autophagy
S. G. van der Grein, K. A. Y. Defourny, H. H. Rabouw…·E. N. M. Nolte-'t Hoen
This study shows the EMCV Leader protein promotes EV-mediated virus release by inducing secretory autophagy, revealing a new role for non-structural viral proteins in non-lytic release.
DOI 10.1038/s41467-022-31181-y