Author

S. Sanchez-Molina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

J. Mora· 2 shared A. Avgustinova· 1 shared A. M. Carcaboso· 1 shared A. M. Espinosa-Oliva· 1 shared C. Lavarino· 1 shared C. Rios-Astorch· 1 shared D. J. Garcia-Dominguez· 1 shared E. Andres-Leon· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

J. Mora

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

KDM6 demethylases mediate EWSR1-FLI1-driven oncogenic transformation in Ewing Sarcoma

E. Figuerola-Bou, C. Rios-Astorch, E. Blanco, M. Sanchez-Jimenez, P. Taboas, G. Fernandez, S. Gomez, O. Munoz, P. Castellano-Escuder, S. Perez-Jaume, E. Prada, S. Mateo-Lozano, N. Riggi, A. Avgustinova, C. Lavarino, , J. Mora

This study identifies KDM6A and KDM6B as EWSR1-FLI1 cofactors in Ewing Sarcoma, showing distinct roles in enhancer activation and tumor growth.

bioRxiv · Jan 24, 2023Cancer Biology

HDAC6 regulates expression of the oncogenic driver EWSR1-FLI1 through the EWSR1 promoter in Ewing sarcoma

D. J. Garcia-Dominguez, N. Hajji, S. Sanchez-Molina, E. Figuerola, R. M. de Pablos, A. M. Espinosa-Oliva, E. Andres-Leon, L. C. Terron-Camero, R. Flores-Campos, G. Pascual-Pasto, M. J. Robles, A. M. Carcaboso, J. Mora, E. de Alava, L. Hontecillas-Prieto

This study shows HDAC6 regulates EWSR1-FLI1 expression in Ewing sarcoma by modulating SP1 acetylation and promoter binding, with HDAC6 inhibition reducing oncogenic activity and enhancing treatment response.

bioRxiv · Jan 4, 2021Cancer Biology