Sort-purification of human CD34+CD90+ cells reduces target cell population and improves lentiviral transduction
S. Radtke, D. Pande, M. Cui, A. M. Perez, Y.-Y. Chan, M. Enstrom, S. Schmuck, A. Berger, T. Eunson, J. E. Adair, H.-P. Kiem
This study compares CD34+CD90+ cell purification to other HSC-enrichment strategies, showing it reduces target cells but improves lentiviral transduction and engraftment.
bioRxiv · Jan 21, 2020Cell Biology