Author

J. E. Adair

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Berger· 1 shared A. M. Perez· 1 shared D. D. Lane· 1 shared D. Pande· 1 shared H.-P. Kiem· 1 shared J. M. P. Castelli· 1 shared K. S. V. Gottimukkala· 1 shared M. Cui· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. Berger

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2 papers

Recent·Most cited

Cas9 RNP Physiochemical Analysis for Enhanced CRISPR-AuNP Assembly and Function

D. D. Lane, K. S. V. Gottimukkala, R. Cunningham, M. E. Cassidy, Y. Jwa, J. M. P. Castelli, J. E. Adair

This paper improves CRISPR-AuNP delivery by optimizing Cas9 RNP loading and nanoparticle surface chemistry, achieving higher RNP loading and uptake in HSPCs but with limited endosomal escape.

bioRxiv · Apr 2, 2024 · PreprintBioengineering

Sort-purification of human CD34+CD90+ cells reduces target cell population and improves lentiviral transduction

S. Radtke, D. Pande, M. Cui, A. M. Perez, Y.-Y. Chan, M. Enstrom, S. Schmuck, A. Berger, T. Eunson, J. E. Adair, H.-P. Kiem

This study compares CD34+CD90+ cell purification to other HSC-enrichment strategies, showing it reduces target cells but improves lentiviral transduction and engraftment.

Molecular Therapy - Methods & Clinical Development · Sep 1, 2020Peer-reviewedCell Biology