Author

S. Sibinelli-Sousa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

E. Bayer-Santos· 2 shared A. Patel· 1 shared B. Y. Matsuyama· 1 shared C. R. Guzzo· 1 shared G. G. Nicastro· 1 shared G. Prehna· 1 shared J. Biboy· 1 shared J. T. Hespanhol· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

E. Bayer-Santos

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2 papers

Recent·Most cited

Molecular characterization of the type VI secretion system effector Tlde1a reveals a structurally altered LD-transpeptidase fold

N. Lorente Cobo, S. Sibinelli-Sousa, J. Biboy, W. Vollmer, E. Bayer-Santos, G. Prehna

This study determines the X-ray crystal structure of Tlde1a, a T6SS effector from Salmonella Typhimurium, revealing its unique LD-transpeptidase fold and functional mechanisms.

bioRxiv · Aug 5, 2022Biochemistry

A Superfamily of T6SS Antibacterial Effectors Displaying L,D-carboxypeptidase Activity Towards Peptidoglycan

S. Sibinelli-Sousa, J. T. Hespanhol, G. G. Nicastro, B. Y. Matsuyama, S. Mesnage, A. Patel, R. F. de Souza, C. R. Guzzo, E. Bayer-Santos

The paper identifies Tae5STM as a T6SS effector with L,D-carboxypeptidase activity that cleaves peptidoglycan, revealing a new superfamily of bacterial effectors involved in interbacterial competition.

bioRxiv · Feb 18, 2020Microbiology