PP6 regulation of Aurora A-TPX2 limits NDC80 phosphorylation and mitotic spindle size
T. Sobajima, K. Kowalczyk, S. Skylakakis, D. Hayward, L. J. Fulcher, C. Neary, C. Batley, S. Kurlekar, E. Roberts, U. Gruneberg, F. A. Barr
The paper shows that PP6 regulates Aurora A-TPX2 to control NDC80 phosphorylation and mitotic spindle size, preventing defective nuclear structure.
bioRxiv · May 23, 2022Cell Biology