BiochemistrybioRxiv
Cooperativity of catalytic and lectin-like domain of T. congolense trans-sialidase modulates its catalytic activity
M. Waespy, T. T. Gbem, N. Dinesh Kumar…·S. Kelm
This study shows that the lectin domain of T. congolense trans-sialidase modulates its catalytic activity by favoring trans-sialylation over hydrolysis when interacting with specific carbohydrates.
DOI 10.1371/journal.pntd.0009585