Nuclear deformation and dynamics of migrating cells in 3D confinement reveal adaptation of pulling and pushing forces
S. Stoeberl, J. Flommersfeld, M. Kreft, M. Benoit, C. Broedersz, J. O. Raedler
This study investigates how nuclear deformation and forces change in migrating cells under 3D confinement, revealing a shift from pulling to pushing mechanisms as channel width decreases.
bioRxiv · Oct 30, 2023Biophysics