Author

S. Szczesny

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:rat· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

A. Dhawan· 2 shared L. N. Paschall· 2 shared A. Tsai· 1 shared B. E. Peterson· 1 shared E. D. Tabdanov· 1 shared E. Tabdanov· 1 shared H. McCarthy· 1 shared K. Pedaprolu· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBioengineering

A. Dhawan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Allograft and Autograft Anterior Cruciate Ligament Reconstructions Exhibit a Similar Biological Response to Cyclic Loading

L. N. Paschall, A. Tsai, E. Tabdanov, A. Dhawan, S. Szczesny

This study compares the biological response of allograft and autograft ACL reconstructions to cyclic loading and finds no difference in remodeling or immune cell markers.

bioRxiv · Mar 20, 2024Bioengineering

Structural Determinants of Tendon Function During Development and Their Sensitivity to Mechanical Stimulation

B. E. Peterson, M. L. Canonicco Castro, H. McCarthy, N. Buckley, N. Dunne, R. A. Rolfe, P. Murphy, S. Szczesny

This study investigates the structural determinants of tendon function during development and their sensitivity to mechanical stimulation, finding that intrafibrillar crosslink formation and fibril elongation are critical and mechanosensitive.

bioRxiv · Aug 25, 2023 · PreprintBioengineering

Cyclic Loading Induces Anabolic and Catabolic Gene Expression in ACLs in a Load-Dependent and Sex-Specific Manner

L. N. Paschall, S. Carrozzi, E. D. Tabdanov, A. Dhawan, S. Szczesny

This study shows cyclic loading induces sex-specific anabolic and catabolic gene expression in ACLs, with male ACLs responding to lower loads and female ACLs downregulating remodeling genes across all loads.

bioRxiv · Nov 11, 2022Bioengineering

A novel, open source, low-cost bioreactor for load-controlled cyclic loading of tendon explants

K. Pedaprolu, S. Szczesny

This paper introduces a low-cost, open-source bioreactor for load-controlled cyclic loading of tendon explants, validated for mouse and rat tissues.

bioRxiv · Mar 16, 2021Bioengineering