Mechanisms of Antimicrobial Agent Cetylpyridinium Chloride Mitochondrial Toxicity in Rodent and Primary Human Cells: Super-resolution Microscopy Reveals Nanostructural Disruption
S. R. Weller, J. E. Burnell, B. M. Aho, B. Obeng, E. L. Ledue, J. K. Shim, S. T. Hess, J. A. Gosse
This study shows that cetylpyridinium chloride (CPC) inhibits mitochondrial ATP production and causes nanostructural mitochondrial defects in rodent and human cells.
bioRxiv · Sep 27, 2022 · PreprintPharmacology & Toxicology