Author

J. K. Shim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

B. Obeng· 2 shared E. L. Ledue· 2 shared J. A. Gosse· 2 shared J. E. Burnell· 2 shared A. Y. B. Vazquez· 1 shared B. E. West· 1 shared B. M. Aho· 1 shared C. M. Potts· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersPharmacology & Toxicology

B. Obeng

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2 papers

Recent·Most cited

Pharmaceutical agent cetylpyridinium chloride inhibits immune mast cell function by interfering with calcium mobilization

B. Obeng, C. M. Potts, B. E. West, J. E. Burnell, P. J. Fleming, J. K. Shim, M. S. Kinney, E. L. Ledue, S. Sangroula, A. Y. B. Vazquez, J. A. Gosse

This study shows that cetylpyridinium chloride inhibits mast cell degranulation by disrupting calcium mobilization without affecting plasma membrane potential or pH.

Food and Chemical Toxicology · Sep 1, 2023Peer-reviewedPharmacology & Toxicology

Mechanisms of Antimicrobial Agent Cetylpyridinium Chloride Mitochondrial Toxicity in Rodent and Primary Human Cells: Super-resolution Microscopy Reveals Nanostructural Disruption

S. R. Weller, J. E. Burnell, B. M. Aho, B. Obeng, E. L. Ledue, J. K. Shim, S. T. Hess, J. A. Gosse

This study shows that cetylpyridinium chloride (CPC) inhibits mitochondrial ATP production and causes nanostructural mitochondrial defects in rodent and human cells.

bioRxiv · Sep 27, 2022 · PreprintPharmacology & Toxicology