Single-cell profiling of tumor-reactive CD4+ T-cells reveals unexpected transcriptomic diversity
A. Magen, J. Nie, T. Ciucci, S. Tamoutounour, Y. Zhao, M. Mehta, B. Tran, D. B. McGavern, S. Hannenhalli, R. Bosselut
The paper uses single-cell RNA sequencing to reveal diverse transcriptomic patterns in CD4+ T cells responding to tumors, highlighting differences from virus responses and potential implications for immunotherapy.
bioRxiv · Feb 8, 2019Immunology