Author

S. Toledo-Patino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2

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Research Focus:chromatin & epigenetic regulation· 2 Approach:statistical model· 2 Approach:mechanistic / dynamical model· 1 Assay:structural biology· 1

Frequent Co-Authors

P. Laurino· 2 shared B. P. S. Chouhan· 1 shared D. Martinez· 1 shared G.-i. Uechi· 1 shared M. H. Gade· 1 shared S. Pascarelli· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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2 shared papersEvolutionary Biology

P. Laurino

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2 papers

Recent·Most cited

Evolutionary BiologybioRxivMay 16, 2022

Insertions and deletions mediated functional divergence of Rossmann fold enzymes

S. Toledo-Patino, S. Pascarelli, G.-i. Uechi, P. Laurino

The paper identifies how insertions and deletions in Rossmann fold enzymes drove coenzyme specificity shifts from NAD(P) to SAM, revealing evolutionary mechanisms for functional divergence.

DOI 10.1073/pnas.2207965119

structural biologystatistical model

𝕏 PostBluesky

Evolutionary BiologybioRxivPreprintAug 17, 2020

Consequences of the divergence of Methionine AdenosylTransferase

B. P. S. Chouhan, M. H. Gade, D. Martinez…·P. Laurino

This study investigates the structural and functional consequences of sequence divergence in archaeal Methionine AdenosylTransferase (MAT) compared to bacterial and eukaryotic MATs.

DOI 10.1101/2020.08.17.254151

statistical modelchromatin & epigenetic regulation

𝕏 PostBluesky